Week 6 closes with the last unbeaten team in the NFC at home in prime time. San Francisco is 5-0 and 4-1 against the spread. Washington is 1-3-1, coming off an overtime tie it nearly fumbled away against the Giants, and its defense ranks in the bottom ten of the league in both success rate and EPA per play.

Betting angle

49ers -7.5 (-108). The board play. Brock Purdy is playing at an MVP level for the No. 2 offense in the league by EPA per play, and Christian McCaffrey is on pace for another 1,500-yard season. Jayden Daniels raises Washington's ceiling and he ran for two scores in his return from a dislocated elbow, but one game back from that injury, on the road, against this pass rush, is a hard ask. San Francisco has won once against the spread as a favorite of 7.5 or more this year and Washington's defense has not stopped a real offense yet. Lay the 7.5 with the home team.

VIA FanDuel, Sports Illustrated, Bleacher Nation.

Key Facts

  • Line: 49ers -7.5 (-108), moneyline 49ers -420 and Commanders +330, total 50.5 at FanDuel
  • Records: 49ers 5-0 and 4-1 ATS. Commanders 1-3-1 and 2-3 ATS.
  • Matchup: San Francisco's No. 2 offense by EPA per play against a bottom ten Washington defense
  • Watch: Monday 8:15 PM ET on ESPN and ABC