Philadelphia opened the season with three straight wins before a 106-93 home loss to Detroit on Sunday. Tyrese Maxey is averaging 28.8 points, and the Sixers have won by at least six points in each of their three wins.

Indiana is banged up. T.J. McConnell is out with a hamstring injury, and Tyrese Haliburton and Andrew Nembhard are questionable. The Pacers lost 110-102 to Milwaukee in their last game and have one home loss in their last four.

Four and a half points is a fair ask for the healthier, better team on the road against a short-handed host. Lay it.

Betting angle

76ers -4.5 (-110). The favorite on the road, laying points. A $10 ticket returns $19.

Watch Wednesday at 6:00 PM CT from Indianapolis.

Key Facts

  • Line: 76ers -4.5 at Pacers, -110
  • Tipoff: Wednesday 6:00 PM CT, Indianapolis
  • Payout: $10 returns $19